Charles Yanofsky is a geneticist who established the “one gene, one protein” relationship. Simply put, Yanofsky’s genetic discoveries serve as the foundation for scientists understanding about DNA and proteins today. His work in molecular biology proved that gene sequences and protein sequences are co-linear. He also helped show that changes in DNA sequence produced changes in protein sequence at corresponding positions. His work also showed how RNA serves as a regulatory molecule in both bacterial and animal cells. He graduated from City College and received his Ph.D. in microbiology from Yale. He began his career at Western Reserve Medical School. He joined the Stanford faculty in 1958 in the Biology Department where he worked for more than fifty years. He was awarded the National Medal of Science in 2003.
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